This article from News-Medical.net piqued my interest this morning----many years ago, I lost a student to pulmonary hypertension. She was only 19 years old, and at that time was one of the youngest patients diagnosed with the condition. This was back about the mid 1980's, and not a lot of research was being done with hormones at the time.
The study detailed in the article has found that low dose estrogen therapy can significantly improve advanced pumonary hypertension-----this is great because many patients with this condition eventually end up needing a lung transplant (Cindy, my student, died waiting for the transplant----you all have signed the donor card, haven't you?) Studies like this further reinforce the fact that hormones affect every system in the body.